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      CommentAuthorrs3gold11
    • CommentTimeFeb 28th 2018
     
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    The Jaguar F Type like exhaust is a perfect match for the charismatic five cylinder engine. At low revs there's a distinctive five pot warble that transforms into a howl near the top of the rev range.The tweaks including a longer seventh speed and more 'coasting' from the stop/start system have also improved fuel consumption by 12.5 per cent over the old RS3 and reduced CO2 emissions by 12 per cent. However, the RS3 will be pricier to run than its nearest rivals to run the Mercedes A45 AMG, for example, emits 161g/km compared to the RS3's 189g/km and returns 40.9mpg.

    AbstractObjective To evaluate the effects of a community based integrated intervention for early prevention and management of chronic obstructive pulmonary disease (COPD) in China.Participants Of 1062 people aged 40 89, 872 (101 with COPD and 771 without COPD) who fulfilled the inclusion and exclusion criteria were allocated to the intervention or the usual care programmes.Intervention Participants randomly assigned to integrated intervention (systematic health education, intensive and individualised intervention, treatment, and rehabilitation) or usual care.Main outcome measures Annual rate of decline in forced expiratory rate in one second (FEV1) before use of bronchodilator.Results Annual rate of decline in FEV1 was significantly lower in the intervention community than the control community, with an adjusted difference of 19 ml/year (95% confidence interval 3 to 36) and 0.9% (0.1% to 1.8%) of predicted values (all P1/FVC (forced vital capacity) ratio (adjusted difference 0.6% (0.1% to 1.2%) P=0.029). There were also higher rates of smoking cessation (21% v 8%, Pv 3%, Pv 11%) did not reach significance between the two communities.Current interventions for COPD (such as smoking cessation, rehabilitation, nutrition support, drug treatments, and psychosocial aids) are mainly carried out in hospitals on a case by case basis among patients who have already developed moderately or severely symptomatic COPD, while little attention has been paid to community based integrated interventions for earlier stages of the disease or before it has developed. Though there has been some progress with case based or hospital based interventions (such as improvements in exercise capacity, forced expiratory volume in one second (FEV1), and health related quality of life, fewer admissions to hospital and acute exacerbations, and lower all cause mortality),6 7 8 9 10 the efficacy of such efforts are limited in the prevention of COPD among the general population in China.


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